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Kidney failure, also known as renal failure, is said to occur when the kidneys lose the ability to carry out their functions properly. Kidney failure can be acute or chronic depending upon various different factors. The treatment for the same is offered at all the leading urology hospitals in Pune.


The kidneys are a pair of bean-shaped organs located on either side of your lower back. These help in cleaning waste products and removingtoxins from the blood which are then thrown out of the body along with urine. They also help to balance the amount of sodium, potassium and calcium in the blood, control blood pressure, balance electrolyte and manage red blood cells production in the body. As per the best doctor in India, if the kidneys fail to function properly it can lead to the accumulation of toxins in the body and pose a serious threat to the patient.


Symptoms and signs

The symptoms of acute renal failure are as under:

  • Internal bleeding
  • Confusion
  • Seizures
  • Elevated blood pressure
  • Abnormal blood and urine tests
  • Coma and Oedema, i.e. swelling of the hand, feet and face.


The symptoms associated with chronic kidney failure in Pune include:

  • Trouble sleeping
  • Oedema
  • Itching
  • Yellow-brown skin
  • Fatigue
  • Headaches
  • Weak bones
  • Muscle twitches and cramps,
  • Easy bruising
  • Seizures
  • Coma
  • Confusion
  • Shortness of breath
  • Angina or chest pains
  • High blood pressure
  • Weight loss for no reason
  • Loss of appetite
  • Nausea
  • Vomiting
  • Anaemia
  • Abnormal blood tests
  • Abnormal urine tests
  • Numbness and tingling.


Various causes of kidney failure:

Kidney failure can be a result of various factors that include:

  • Impaired blood flow to the kidneys


A sudden loss of blood flow to your kidneys can cause kidney failure. Diseases and conditions that cause loss of blood flow to the kidneys include:

  • Heart attack
  • Heart disease
  • Blood or fluid loss
  • Dehydration
  • Scarring of the liver or liver failure
  • Severe burn
  • Anaphylaxis (severe allergic reaction)
  • Severe infection, such as sepsis
  • Use of aspirin, ibuprofen, naproxen sodium or related drugs

High blood pressure and anti-inflammatory medications are also known to limit blood flow to the kidneys.


  • Urinary obstructions

Toxins can build up and burden the kidneys when the body is unable to eliminate urine. Diseases and conditions that block the passageways of urine out of the body and can lead to acute kidney injury are mentioned below:

  • Cancers like prostate cancer, colon cancer, cervical cancer and bladder cancer
  • Kidney stones
  • Enlarged prostate
  • Blood clots within the urinary tract
  • Damage to nerves that control bladder


  • Damage to kidney

Some other problems that may cause damage to kidney eventually leading to kidney failure include the following:

  • A blood clot in and around the veins and arteries surrounding your kidneys
  • A severe infection
  • An overload of toxins from heavy metals
  • Lupus, i.e. an immune system disorder that can cause glomerulonephritis
  • Glomerulonephritis, i.e. the inflammation of the tiny filters in the kidneys (glomeruli)
  • Toxins such as heavy drugs and alcohol
  • Cholesterol deposits as they may block blood flow to the kidney
  • Vasculitis that is an inflammation of blood vessels
  • Certain antibiotics
  • Uncontrolled diabetes
  • Dyes used in some imaging tests and medications, such as certain chemotherapy drugs, antibiotics
  • Thrombotic thrombocytopenic purpura, a rare blood disorder that causes blood clots in small vessels
  • Hemolytic uremic syndrome, which involves the breakdown of red blood cells following a bacterial infection, usually of the intestines
  • Multiple myeloma, a cancer of the plasma cells in your bone marrow
  • Scleroderma that is a group of rare diseases that affect the skin and connective tissues
  • Rhabdomyolysis that is muscle tissue breakdown that leads to kidney damage. It is caused by toxins from muscle tissue destruction
  • Hemolytic uremic syndrome is a condition that results from premature destruction of red blood cells
  • Tumour lysis syndrome that is the breakdown of tumour cells which leads to the release of toxins that can cause renal injury