Pre Transplant in Thane

Before undergoing transplant, you may need to undergo rigorous evaluation, which includes:

  • CT scans of the head, chest, and abdomen.
  • X-rays of the upper GI tract.
  • X-ray of the small bowel.
  • Ultrasound for detailed visualization of internal organs.
  • Endoscopy for a comprehensive examination.
Blood and Genetic Testing
  • Blood tests, including gene compatibility assessments.
  • Cancer screening tests to evaluate overall health.
Medical and Psychological Assessment
  • General health exam, including physical examination.
  • Social and psychological evaluation to gauge stress, financial factors, and support systems.
Additional Tests
  • Stress tests, pulmonary function testing, heart catheterization, and motility studies.
Colonoscopy and Ultrasound
  • Colonoscopy to inspect the entire colon.
  • Ultrasound to create internal organ images using sound waves.

Colonoscopy helps the doctor to look inside the entire colon for any abnormality. In this procedure, a long, flexible tube (colonoscope) is inserted into the rectum. There is a tiny video camera at the tip of the tube that gives the pictures.

Looking for the Pre Transplant in Thane

Pre-Transplant in Thane

Before receiving an intestinal transplant in Thane, find a doctor and be informed of the waiting period. Due to a higher demand for transplants than available organs, the waiting list in India is considerably long. While waitlisted, your doctor will initiate necessary treatments to keep you stable and prepare for the impending transplant. Regularly update your doctor on any health changes.

Intestinal Transplant Process

Upon organ availability, the hospital will urgently admit you and provide information. Tests and evaluations are conducted to assess your health for surgery. Anesthesia is administered in the operating theater before the procedure. Some patients may require ventilator support based on their health conditions.

The surgery involves making an incision, evaluating the abdomen for abnormalities, and removing the intestine. The donated organ(s) are then placed in the abdomen. A stoma is created for monitoring, and a Gastrojejunostomy tube may be inserted.

After the procedure, the incision is closed.

Surgical Complications

During or shortly after intestinal transplant surgery, certain complications may arise, including:

  • Wound Infection
  • Blood Clot Formation
    • Artery or vein clotting in the lungs, heart, spleen, pancreas, or liver.
  • Diabetes Development
  • Bile Leakage from Bile Ducts
  • Uncontrollable Bleeding

Immunosuppressant-Related Complications

To facilitate the adjustment of the new organ in the body, immunosuppressants are prescribed. However, this comes with potential complications, exposing the recipient to various infectious diseases.

  • Rejection In some cases, the body may not accept the new organ, leading to potential dysfunction. The immune system may recognize the transplanted organ as foreign, increasing the risk of rejection.
  • Side Effects of Anti-Rejection Medications Medications prescribed for liver function and overall health can result in significant side effects, including:
    • Weight Gain
    • High Blood Pressure
    • Kidney Damage
    • Cholesterol Imbalance

Vascular Complications

  • Thrombosis: Formation of clots in the artery or vein of the newly transplanted intestine, causing a halt in blood supply.
  • Bleeding: High risk of internal bleeding associated with major surgeries, potentially requiring blood transfusion and additional surgical intervention.
  • Leak: Occasional leaks may occur where the new intestine is connected to the recipient's organ, necessitating surgical intervention to rectify the issue.

Laboratory evaluation

Prior to the transplant, a comprehensive laboratory evaluation is conducted, including:

  • Blood Group (ABO): To determine compatibility with a potential donor.
  • Complete Blood Count (CBC): To assess the degree of anemia and planning pre-transplant treatment.
  • Urine Routine and Culture: To rule out urinary tract infection and assess proteinuria levels.
  • Liver Function Tests: To detect any impairment in liver function.
  • Blood Glucose: To evaluate diabetes status and control.
  • Lipid Profile: To identify abnormalities and plan appropriate treatment.
  • Renal Function Tests: To assess preoperative electrolytes for fitness.
  • Coagulation Tests (PT/PTT/BT): To rule out bleeding and coagulation abnormalities.
  • Viral Disease Screening (HbsAg/HCV/HIV/EBV/CMV IgG): To detect and treat viral diseases, activating prophylaxis as needed after transplant.
  • Tissue Typing/HLA: To determine compatibility between the donor and recipient.
  • Lymphocyte Cross-Match: To identify antibodies against donor T and B cells, assessing compatibility and the risk of organ rejection.
  • Uroflowmetry Post-Void Residue: To assess obstruction and bladder status before transplant.
  • CT Scan/Iliofemoral Vessel Doppler: To detect kidney stones or calcifications in iliac blood vessels where donor kidney vessels will be joined.
  • Gastrointestinal Endoscopy: To be required for selected patients showing positive stool occult blood or a history of peptic ulcers.

Donor Evaluation:

Donors undergo thorough medical evaluations to ensure robust health and optimal compatibility. Tests include cardiac and pulmonary evaluations, blood group compatibility, and cross-match testing to assess immunological risks, as mandated by the Human Organ and Tissue Transplant Act.

Medical Evaluation for Donors

Medical evaluation ensures donors are in good health, free from diseases transmissible to the recipient, and can safely undergo kidney donation. Cardiac and pulmonary evaluations, and a battery of relevant medical tests, contribute to a comprehensive assessment.

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