One of India's largest private quaternary care hospitals, has Haematology & Bone Marrow Transplant (BMT) as a core component of its services. Our goal is to make bone marrow transplants more accessible as a potential treatment for individuals with complicated blood diseases.
Our team of dedicated and highly skilled transplant specialists are committed to providing comprehensive care to all our patients, following the principles of innovation, teamwork, confidentiality, empathy, and integrity. We strive to deliver the highest standards of care in Haematology & BMT, utilizing advanced techniques and technologies to achieve the best possible outcomes for our patients.
Our team of qualified experts has successfully completed hundreds of transplants for patients from around the world.
We use a multidisciplinary approach when treating patients with cancer or blood illnesses like leukemia, lymphoma, myeloma, and other blood disorders requiring transplants. Each patient, regardless of age, receives a customized treatment plan that is tailored to their changing needs before, during, and after the transplant.
The Centre boasts state-of-the-art facilities and a highly qualified staff with worldwide training. Our modern transfusion services, cutting-edge labs, fully-stocked radiation oncology center, and other resources are in place to provide the best possible care to our patients.
Centre’s Key Features Include:
Department Of Transfusion Medicine
Laboratory Services Offered:
A Full-Service Offering
Numerous blood illnesses, including acute and chronic leukaemia, myelomas, lymphomas, myeloproliferative and lymphoproliferative disorders, marrow failure syndromes, and coagulation disorders are diagnosed and treated at the Centre.
For a variety of benign and malignant disorders, we offer a comprehensive range of facilities and services, including cord blood stem cell, peripheral blood, and allogeneic and autologous bone marrow transplants.
Bone marrow transplant, also known as hematopoietic stem cell transplant (HSCT), replaces diseased bone marrow with healthy stem cells. The first step is collecting stem cells from either peripheral blood or bone marrow. These cells are used in transplantation to treat blood-related disorders like leukemia, lymphoma, and autoimmune diseases.
Bone marrow, located within the central cavities of bones, is a soft and spongy tissue responsible for the production of blood cells. It contains microscopic compartments that house primitive cells known as stem cells. These stem cells possess the ability to differentiate into various types of blood cells, including red blood cells (which carry oxygen), white blood cells (which fight infections), and platelets (which aid in blood clotting). This unique capability of stem cells to generate different types of blood cells is crucial for maintaining a healthy blood supply and proper functioning of the body.
Red and yellow varieties of bone marrow are the most common. The majority of children's bone marrow is red and abundant in stem cells. In adolescents, however, a large portion of the bone marrow is transformed into yellow marrow due to adipose cell infiltration. Red marrow is typically restricted to a few bones in adolescents, including the hip bones, breast bone, ribs, shoulder blades, cranium, backbone, arm, and thigh ends.
The detection of blood cancers and their treatment with chemotherapy and other modalities is required as per the case.
Benign Haematology- Benign Disorders Of Blood
The process of bone marrow transplantation may differ depending on the type of donor and transplant procedure used. In general, there are two kinds of transplant procedures:
Types Of Allogeneic Bone Marrow Transplant:
The harvested bone marrow or stem cells are filtered to remove fat or other particles, transported to the laboratory for processing, and then tallied, screened, and prepared for infusion. The type of transplant a patient must undergo depends on his or her specific medical requirements. A physician will evaluate the patient's medical condition and recommend an appropriate treatment plan. The purpose of a bone marrow transplant is to treat a variety of blood disorders and some forms of malignancy.
BMT Process Consists Of Three Main Phases Which Include:
Here's a rundown of everything you need to know about the transplant procedure. The guide is structured into six sections, beginning with how to prepare for the trip and ending with what to expect along the route.
STEP 1: Preparation The preparation phase begins when the patient arrives at the BMT Centre, with medical assessment, guidance, informed consent, and other preceding activities.
STEP 2: Bone-Marrow/Stem Cells Harvest:Apheresis is a technique for extracting stem cells from bone marrow or peripheral blood. Stem cells are retrieved from the donor in an allogeneic transplant, whereas stem cells are collected from the patient in an autologous transplant.
STEP 3: Conditioning:Conditioning is the initial stage before transplantation. In this procedure, the patient receives either chemotherapy, radiation therapy, or a combination of the two. The bone marrow function is destroyed by chemotherapy and radiation therapy doses that have the highest chance of curing the disease. Depending on the timetable for administering the chemotherapeutic medicines and radiation therapy, some conditioning treatment may be given in an outpatient setting, potentially cutting the length of the inpatient stay. The pre-BMT phase consists of the following: preparation, stem cell harvest, and conditioning.
STEP 4: Transplant:In this stage, the infusion of donor bone marrow or stem cells takes place right after the conditioning regimen has been finished. This is similar to a blood transfusion. The duration beyond the transplant day is considered as the post BMT phase.
STEP 5: Awaiting Engraftment (New Cell Growth):This stage entails close monitoring, supportive therapy, and complication management while waiting for grafting indications.
STEP 6: Early Recovery and Engraftment: In roughly 2 to 3 weeks following the transplant, it is possible to anticipate signs that new bone marrow or stem cells are grafting (growing and developing). The patient will continue to receive close observation and supportive care, and preparations for their return home will begin.
STEP 7: Long-Term Recovery: This step entails releasing the patient from the facility, talking about any lingering clinical issues, and reestablishing daily routines. Regular follow-up visits are advised for patients to prevent any long-term consequences.
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