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Pre Transplant in Dombivli
Before proceeding with an intestine transplant, a detailed and structured pre-transplant evaluation is essential. This process helps determine whether the patient is medically fit for surgery and ensures the best possible outcomes from intestine transplant treatment in Dombivli.
Imaging and Diagnostic Tests
A series of imaging investigations is carried out to assess the condition of the intestine and other vital organs. These include:
- CT scans of the head, chest, and abdomen to evaluate overall anatomy and organ status
- X-rays of the upper gastrointestinal tract to assess swallowing and stomach function
- X-ray imaging of the small bowel to identify structural abnormalities
- Ultrasound scans to obtain detailed images of internal organs
- Endoscopy for a thorough examination of the digestive tract
These tests help the gastrointestinal surgeon in Dombivli plan the transplant procedure with precision.
Blood and Genetic Testing
Blood investigations form a crucial part of the pre-transplant work-up. These include:
- Routine and specialised blood tests to assess overall health
- Genetic and tissue compatibility testing to evaluate donor–recipient matching
- Cancer screening tests to rule out underlying malignancies
Medical and Psychological Assessment
A complete medical and psychosocial evaluation is performed to ensure holistic readiness for transplant surgery. This includes:
- A detailed physical examination to assess general health
- Social and psychological evaluation to understand stress levels, emotional readiness, financial considerations, and availability of family support
This step is vital for long-term recovery after intestine surgery in Dombivli.
Additional Functional Tests
To further assess surgical fitness, patients may undergo:
- Cardiac stress testing
- Pulmonary function tests
- Heart catheterisation, if required
- Gastrointestinal motility studies
Colonoscopy and Ultrasound
- Colonoscopy is performed to examine the entire colon for abnormalities
- Ultrasound imaging is used to visualise internal organs using sound waves
Looking for the Pre Transplant in Dombivli
Waiting Period Before Intestinal Transplant
Before receiving an intestine transplant in Dombivli, patients are registered on a transplant waiting list. Due to the high demand for donor organs, waiting periods can be prolonged. During this time, the treating team initiates supportive treatments to stabilise the patient and prepare the body for transplant surgery.
Patients are advised to remain in regular contact with their doctor and report any changes in health promptly.
Intestinal Transplant Procedure
Once a suitable organ becomes available, the patient is urgently admitted to the intestine transplant hospital in Dombivli. Final tests are conducted to confirm surgical readiness. Anaesthesia is administered in the operating theatre, and some patients may require ventilator support depending on their condition.
The surgery involves making an abdominal incision, carefully examining the abdominal cavity, and removing the diseased intestine. The donor intestine is then placed and connected. A stoma may be created for close monitoring, and a gastrojejunostomy tube may be inserted to support nutrition. The incision is then closed.
Possible Surgical Complications
Certain complications can occur during or shortly after surgery, including:
- Wound infections
- Formation of blood clots in arteries or veins affecting the lungs, heart, liver, spleen, or pancreas
- Development of diabetes
- Leakage of bile from the bile ducts
- Excessive or uncontrolled bleeding
Immunosuppressant-Related Complications
To prevent rejection of the transplanted intestine, immunosuppressant medications are prescribed. While essential, these medicines may increase the risk of infections and other side effects.
Risk of Rejection
In some cases, the immune system may identify the new intestine as foreign, which can affect organ function and lead to rejection.
Side Effects of Anti-Rejection Medicines
These may include:
- Weight gain
- High blood pressure
- Kidney damage
- Cholesterol imbalance
Vascular Complications
- Thrombosis: Blood clots may form in the artery or vein supplying the transplanted intestine, potentially stopping blood flow.
- Bleeding: Major surgery carries a risk of internal bleeding, which may require blood transfusions or additional procedures.
- Anastomotic Leak: Leaks can occur at the site where the donor intestine is connected, sometimes requiring surgical correction.
Laboratory Evaluation Before Transplant
A comprehensive laboratory work-up is completed prior to surgery, including:
- Blood group (ABO) testing for donor compatibility
- Complete blood count (CBC) to assess anaemia<
- Urine routine and culture to rule out infection
- Liver function tests
- Blood glucose testing to evaluate diabetes control
- Lipid profile
- Renal function and electrolyte tests
- Coagulation tests (PT, PTT, BT)
- Viral screening for hepatitis B, hepatitis C, HIV, EBV, and CMV
- Tissue typing and HLA testing
- Lymphocyte cross-match to assess rejection risk
Additional tests such as uroflowmetry, CT scans, Doppler studies, and gastrointestinal endoscopy may be advised for selected patients.
Donor Evaluation
Donors undergo strict medical evaluation to ensure safety and compatibility, as mandated under the Human Organ and Tissue Transplant Act. This includes:
- Cardiac and pulmonary assessments
- Blood group compatibility testing
- Cross-match studies to assess immunological risk
Only donors who are medically fit and free from transmissible diseases are considered suitable for intestinal donation.
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